Description
- Karuna Health SAM-e Plus contains the tosylate form of SAM-e as used extensively in clinical trials, and includes several other ingredients found in studies to support and facilitate these functions.
- Over a decade of rigorous clinical studies in Europe and elsewhere have established SAM-e (S-adenosyl-L-methionine, an essential methylation and transulfuration cofactor) as a useful tool for supporting normal mood regulation, and joint and liver health. SAM-e increases cell membrane fluidity, up-regulates neurotransmitter receptor number, and enhances neurotransmitter receptor affinity.
- SAM-e supports healthy joints both by increasing the number of articular chondrocytes, and by stimulating the synthesis of protective sulfated proteoglycans therein. SAM-e also protects synovial cells against pro-inflammatory prostanoids, and blocks enzymes that degrade cartilage.
- SAM-e is a precursor of the critical antioxidant glutathione, a key molecule in the detoxification process in the liver.
Suggested Use:
Two to four capsules daily, preferably morning and evening, or as directed.
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving … %DV
Niacin (Niacinamide) ... 30 mg … 188%
Vitamin B6 (Pyridoxine HCl) ... 2 mg ... 188%
Folic Acid ... 669 mcg DFE (400 mcg folic acid) ... 167%
Vitamin B12 (Methylcobalamin) ... 20 mcg ... 833%
Choline Bitartrate ... 50 mg ... 9%
SAM-e (S-adenosylmethionine) ... 400 mg ... †
† Daily Value (DV) not established
Other Ingredients:
DR cap, (Hypromellose & gellan), silica, magnesium stearate (vegetable)
*These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to treat, mitigate, diagnose or cure any disease.



