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Bioclinic Naturals Vitamin K2, D3 & A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation.
This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.
Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles.
Supplementation is associated with a well-established reduction in osteoporotic fracture.
Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate.
Vitamin K is now recognized as being necessary not only for coagulation, but for the carboxylation of enzymes critical for both bone and blood vessel health.
Indeed, meta-analysis has shown improvement in vertebral BMD and reduction in fracture among post-menopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women.
The naturally derived MK-7 form in Vitamin K2, D3 & A has a longer half-life than any other form.
Potent physiological balance of key fat-soluble vitamins, A, D, and K, critical to bone health.
Contains vitamin K2 (MK-7), the most bioactive and long-lasting form.
MK-7 shown to increases vertebral BMD among postmenopausal women.
Provides vitamin D3, shown to be more effective than D2 in maintaining blood levels of 25-OH vitamin D.
Optimal form of vitamin A, palmitate, bypasses impaired conversion of carotenoids (affects nearly half the population).
Suitable for vegetarians.
1 serving (0.25 ml) per day or as directed by a health care practitioner.